Main Findings
To our knowledge, this is the first research finding that ANGPTL4
expression level in ovarian GCs had a significant increase in PCOS
patients compared with women with regular ovulatory cycle. In addition,
we also found that the expression level of ANGPTL4 was positively
correlated with AMH, HOMA-IR, LDL/HDL, ApoB/ApoAI and TC/HDL after
correlation analysis with the corresponding clinical data in all
participants. According to the results of multiple liner regression
analysis, ANGPTL4 expression was also related to PCOS, FBG, FINS,
HOMA-IR, TG and ApoAI. Those showed that the ANGPTL4 expression in
ovarian GCs was closely associated with glucose and lipid metabolism in
PCOS.