Main Findings
To our knowledge, this is the first research finding that ANGPTL4 expression level in ovarian GCs had a significant increase in PCOS patients compared with women with regular ovulatory cycle. In addition, we also found that the expression level of ANGPTL4 was positively correlated with AMH, HOMA-IR, LDL/HDL, ApoB/ApoAI and TC/HDL after correlation analysis with the corresponding clinical data in all participants. According to the results of multiple liner regression analysis, ANGPTL4 expression was also related to PCOS, FBG, FINS, HOMA-IR, TG and ApoAI. Those showed that the ANGPTL4 expression in ovarian GCs was closely associated with glucose and lipid metabolism in PCOS.