LIMITATIONS.
Our study was an analysis from clinical database, from single referral
center with limited number of patients and cardiovascular events.
Diastolic parameters are difficult to assess in valvular patients with
volume overload; however, they have been analyzed in other volume
overload valvulopathies, such as mitral regurgitation, with confirmed
prognostic value. Due to the retrospective nature of the study, LA
auto-strain was not available throughout the sample. Thus, further
prospective studies are required to validate our findings.