Individual- and group-level BOLD fMRI analyses
On the first-level the SID task was modeled in line with previous
studies (2, 60-62), including condition- (social reward, social
punishment, neutral) and phase- (anticipation, outcome) specific
regressors (see supplementary method ). On the group level
effects of treatment were examined employing mixed ANOVA analyses with
the factors (condition, treatment) for each phase. Based on our a priori
regional hypotheses the analyses focused on the ventral striatum (VS),
dorsal striatum (DS) (63) and VTA (64) as Regions of Interest (ROIs).