Quantitative variables 11 Explain how quantitative variables were handled in the analyses. If applicable, describe which groupings were chosen and why 6-10
Statistical methods 12 (a) Describe all statistical methods, including those used to control for confounding 9,10
(b) Describe any methods used to examine subgroups and interactions N.A.
(c) Explain how missing data were addressed N.A.
(d) Cohort study—If applicable, explain how loss to follow-up was addressed Case-control study—If applicable, explain how matching of cases and controls was addressed Cross-sectional study—If applicable, describe analytical methods taking account of sampling strategy
N.A.
(e) Describe any sensitivity analyses N.A.
Results Results Results Results Results
Participants 13* (a) Report numbers of individuals at each stage of study—eg numbers potentially eligible, examined for eligibility, confirmed eligible, included in the study, completing follow-up, and analysed 11, table 1
(b) Give reasons for non-participation at each stage 12
(c) Consider use of a flow diagram Table 3
Descriptive data 14* (a) Give characteristics of study participants (eg demographic, clinical, social) and information on exposures and potential confounders Table 1
(b) Indicate number of participants with missing data for each variable of interest N.A.
(c) Cohort study—Summarise follow-up time (eg, average and total amount) N.A.
Outcome data 15* Cohort study—Report numbers of outcome events or summary measures over time
Case-control study—Report numbers in each exposure category, or summary measures of exposure 10-13
Cross-sectional study—Report numbers of outcome events or summary measures
Main results 16 (a) Give unadjusted estimates and, if applicable, confounder-adjusted estimates and their precision (eg, 95% confidence interval). Make clear which confounders were adjusted for and why they were included 11
(b) Report category boundaries when continuous variables were categorized N.A.
(c) If relevant, consider translating estimates of relative risk into absolute risk for a meaningful time period N.A.