The expression of serum inflammatory mediators were up-regulated
in OF patients
The occurrence of the vast majority of diseases is caused by
inflammation, so we carried out the detection of inflammatory mediators
in the serum of OF patients, and the results showed that compare with
NC, the OF patients have a higher expression of inflammatory mediators
IL-1 (0.3638±0.01917pg/mL vs 0.131±0.011pg/mL, P<0.001), IL-6
(133.7±10.94pg/mL vs 79.59±8.775pg/mL, P<0.001) and TNF-α
(1.57±0.14pg/mL vs 6.11±0.77pg/mL ) (Figure 1).