Figure 4. Functions of PF Th17 subsets. (A & B) GM-CSF
expression in IL-17RE+CD27- subset,
IL-17RE+CD27+ subset, and
IL-17RE-CD27- subset. Representative
flow cytometry plots are shown in (A), and statistics of the frequencies
of GM-CSF+ cells are shown in (B). (C)Relative mRNA levels of IL22 in the three subsets. N=5 per group.
Kruskal-Wallis test. (D) Flow cytometry plots showing cell
cycle measured by staining with Hoechst 33342 and Pyronin Y. *:p <0.05; **: p <0.01.