Study group
Fifty consecutive patients undergoing elective CABG in the Okmeydanı
Training and Research Hospital were included in this prospective study.
Subjects with a history of bleeding diathesis or abnormal preoperative
coagulation test results (international normalized ratio ≥ 1.3,
activated partial thromboplastin time >40 s) and those with
chronic liver disease were excluded. Subjects scheduled for
re-operation, and those in whom postoperative hemodynamic support with
intraaortic balloon pump (IABP) or extracorporeal membrane oxygenation
(ECMO) were required, were also excluded. Written informed consent was
obtained from all participants. The study was approved by the
institutional review board and was conducted in accordance with the
Helsinki declaration (No:48670771-514.10).