Study group
Fifty consecutive patients undergoing elective CABG in the Okmeydanı Training and Research Hospital were included in this prospective study. Subjects with a history of bleeding diathesis or abnormal preoperative coagulation test results (international normalized ratio ≥ 1.3, activated partial thromboplastin time >40 s) and those with chronic liver disease were excluded. Subjects scheduled for re-operation, and those in whom postoperative hemodynamic support with intraaortic balloon pump (IABP) or extracorporeal membrane oxygenation (ECMO) were required, were also excluded. Written informed consent was obtained from all participants. The study was approved by the institutional review board and was conducted in accordance with the Helsinki declaration (No:48670771-514.10).