Insert Figure 1 and Table 4
Comparison of functional data between the treatment and no-treatment
group showed no significant differences in activation areas before
olfactory training, after performing a two-sample T-test. After the
intervention, fMRI showed an increased amount of activating areas in the
treatment group in comparison with the no-treatment group. Nonetheless,
no significant differences were determined. Although no differences were
found in the prior analysis, statistical significance was achieved when
we compared the activation areas after olfactory training with the
activation areas before treatment in the intervention group, using each
patient as its own control. Before training, only five cluster areas
activated. In contrast, after training, nine cluster areas activated in
the treatment group, and one big voxel cluster in the cerebellum area
(Table 5).
All patients showed an activation of the trigeminal related areas, like
the precentral gyrus, brainstem, insula, and pars triangularis on their
first fMRI. The activation of the areas described beforehand could
suggest trigeminal pathway indemnity.