Ethics statement
Written informed consent was obtained from the patients participating in the study before collecting 2ml of their peripheral blood for the experiment. The patients were recruited in this study of clinical and molecular diagnosis of inherited heart disease patients related genes approved by the Institutional Ethics Committees at Third Xiangya Hospital of Central South University. Genomic DNA was extracted from peripheral blood samples following the manufacturer’s standard procedure using the HiPure Blood DNA Midi Kit III (Magen, Guangzhou, China).