Conclusion
In this work, we found that one novel and five recorded mutations in four genes related to inherited heart diseases. The targeted next-generation sequencing was applied in this study to detect the candidate mutations. NGS has been proved to have considerable potential for both clinic and research use. The exon capture followed by NovaSeq 6000 sequencing was specifically used in our study. Combined applications of this platform and bioinformatics are very promising and effective methods for molecular screening of patients with inherited heard diseases, but it still remains that deficiencies on accuracy and stability need to be further investigated.