The intention of this exertion is to inspect the flow heat and mass transfer of unsteady magnetite Casson nanofluid over a wedge. The peak theme of thermal radiation and chemical reaction are also incorporated. Slip effects are also assumed near the surface of the wedge along with the convective boundary restrictions. The governing equations are transmuted into dimensionless form first, the famous shooting technique is implemented. The obtained numerical outcomes are exhibited through graphs and tables. Fascinating features of various emerging parameters in flow, heat and nanoparticle concentration are discussed.