Variables
The patient variables (Table 1) were processed both from the structured and coded EHR data (visits, procedure codes and diagnoses of the patients) and free clinical texts (diagnoses and comorbidities, Figure S2, Table S1). Comorbidity-related variables were obtained from ICD-10 codes (Table S3) and by using validated keyword-based information extraction from free clinical texts (Please see further methods in this article’s supporting information). For asthma we used ICD-10 codes J45., which is doctor-diagnosed lung-function test -confirmed asthma. NERD diagnosis was obtained from EHR text and was based on typical history of airway symptoms after ingestion of NSAID ± challenge test confirmation of NERD.