Acknowledgments
The authors acknowledge the patients and their families for their cooperation. The authors thank Prof. Dong-sheng Fan and Ze-xu Chen for their kind assistance in critically revising the manuscript.
Author contributions
All authors designed the study and collected the clinical and genetic data of the two patients. Jia-tong Li and Si-qi Dong completed the collection and assessment of previous publications independently and wrote the manuscript. Xiang-jun Chen revised the manuscript. All authors read and approved the manuscript.