Prognostic and predictive factors
The estimation of 5 and 10- year survival is 38% and 32% respectively(2). For overall survival, among many factors such as patient’s age at the presentation, tumor size, histopathologic grade and subtype, atypia, mitotic activity, type and extent of surgery, and surgical margin status, only the tumor size less than 5cm and fibroblastic subtype have been more accepted as favorable factors and most reliable ones among many of the series(1,2,3,48). Furthermore, surgical margin status and the type of surgery (local excision vs mastectomy) can be predictive factors for local recurrence. The most common sites for metastasis are the lung, bone, skin, and heart consequently(2,20,26,41,49).