Conclusions
This study demonstrated that low-DII-score formula (which contains vitamins, salts and nutrients with anti-oxidant properties) may improve inflammatory factors (hs-CRP), metabolic biomarkers, and clinical outcomes in critically ill TBI patients admitted in the intensive care unit. However, despite the important clinical results of the present study, it seems that the formula used in this study needs to be evaluated in larger patient groups and multi-centre trials in order to produce more robust and generalizable results, that can help guide clinical practice.