Acknowledgments
The authors thank the GESR of the Lombardi Comprehensive Cancer Center
(Washington DC, USA) for performing the array-CGH slides washes and
scanning, and the Center for Advanced Technologies in Fluorescence
(CTAF) at the Federal University of Paraná (Curitiba, PR, Brazil) for
performing FISH confocal microscopy imaging. We also acknowledge CAPES
for Dr. Bruno C. Feltes postdoctoral fellowship and Ms. Akanksha Mahajan
(MSc) for the technical support with array-CGH and FISH analyses.
Ethics approval and consent to participate: The present study
was approved by the Human Research Ethics Committee (HPP/PR -
CEP0518-07/2007; amendment 2014) of the Pequeno PrÃncipe Hospital
(Curitiba, PR, Brazil). The analysis of the human samples used in the
present study was performed following the international and national
regulations in accordance with the Declaration of Helsinki.