Funding:
This work was supported by
National Natural Science
Foundation of China, grant number 81572807 and 81872329; and
by
Chongqing
Municipal Education Commission of Science and Technology Research
Project of China, grant number: KJZD-K201800403
Acknowledgements:
We would like to thank all team members involved in tumor immunotherapy
project at Chongqing Key Laboratory of Basic and Translational Research
of Tumor Immunology, Chongqing Medical University for their
technological assistance and help in developing this article. We thank
Professor Tatsuhiko Ozawac, Eiji Kobayashic and Hiroyuki Kishi for help
with experiments. We also thank all healthy individuals participated in
this study. We appreciate supporter Mr. Yuling Feng providing Chongqing
Medical University fund (X4457).
Conflict of Interests
The authors declare no competing interests.