Funding:
This work was supported by National Natural Science Foundation of China, grant number 81572807 and 81872329; and by Chongqing Municipal Education Commission of Science and Technology Research Project of China, grant number: KJZD-K201800403
Acknowledgements:
We would like to thank all team members involved in tumor immunotherapy project at Chongqing Key Laboratory of Basic and Translational Research of Tumor Immunology, Chongqing Medical University for their technological assistance and help in developing this article. We thank Professor Tatsuhiko Ozawac, Eiji Kobayashic and Hiroyuki Kishi for help with experiments. We also thank all healthy individuals participated in this study. We appreciate supporter Mr. Yuling Feng providing Chongqing Medical University fund (X4457).
Conflict of Interests
The authors declare no competing interests.