Image interpretation
For conventional colposcopy, the
colposcopists recorded the results of the colposcopy based on the
staining of acetic acid and iodine solution and gave
the
colposcopic impression
(normal/benign; low grade; high
grade; cancer) before biopsy taking. Colposcopy-directed biopsy was
taken as the gold standard to assess visual inspection readings. As for
fluorescence colposcope, in addition to the visible fluorescent signal,
we added a regions of interest (ROI) tool to the image acquisition
software to calculate the SBR of a certain site in real time. Each
sampling site got an SBR value. The larger the value, the greater the
possibility of cervical intraepithelial neoplasia.