Trial design
This was a prospective non-blinded randomized controlled trial,
performed at Colposcopy Center of Department of Obstetrics and
Gynecology, Tongji Hospital, Wuhan, China, which was a tertiary
university hospital with a particular clinical and research interest in
the cervical diseases. The study protocols were reviewed and approved by
Ethics Committee of Tongji Hospital on September 14, 2017 (reference No.
TJ-IRB20170903). And the trial was prospectively registered at
ClinicalTrials.gov (NCT
03321461, Date: October 25, 2017).