loading page

SARS-CoV-2 mass vaccination: Urgent questions on vaccine safety that demand answers from international health agencies, regulatory authorities, governments and vaccine developers
  • +47
  • Roxana Bruno,
  • Peter A Mccullough,
  • Teresa Forcades I Vila,
  • Alexandra Henrion-Caude,
  • Teresa García-Gasca,
  • Galina P Zaitzeva,
  • Sally Priester,
  • María J Martínez Albarracín,
  • Alejandro Sousa-Escandon,
  • Fernando López Mirones,
  • Bartomeu Payeras Cifre,
  • Almudena Zaragoza Velilla,
  • Leopoldo M Borini,
  • Mario Mas,
  • Ramiro Salazar,
  • Edgardo Schinder,
  • Eduardo A Yahbes,
  • Marcela Witt,
  • Mariana Salmeron,
  • Patricia Fernández,
  • Miriam M Marchesini,
  • Alberto J Kajihara,
  • Marisol V De La Riva,
  • Patricia J Chimeno,
  • Paola A Grellet,
  • Matelda Lisdero,
  • Pamela Mas,
  • Abelardo J Gatica Baudo,
  • Elisabeth Retamoza,
  • Oscar Botta,
  • Chinda C Brandolino,
  • Javier Sciuto,
  • Mario Cabrera Avivar,
  • Mauricio Castillo,
  • Patricio Villarroel,
  • Emilia P Poblete Rojas,
  • Bárbara Aguayo,
  • Dan I Macías Flores,
  • Jose V Rossell,
  • Julio C Sarmiento,
  • Victor Andrade-Sotomayor,
  • Wilfredo R Stokes Baltazar,
  • Virna Cedeño Escobar,
  • Ulises Arrúa,
  • Atilio Farina del Río,
  • Tatiana Campos Esquivel,
  • Patricia Callisperis,
  • María Eugenia Barrientos,
  • Christian Fiala,
  • Karina Acevedo-Whitehouse
Roxana Bruno
Epidemiólogos Argentinos Metadisciplinarios
Peter A Mccullough
Baylor University Medical Center
Teresa Forcades I Vila
Monestir de Sant Benet de Montserrat
Alexandra Henrion-Caude
Simplissima International Research Institute, Mauritius.
Teresa García-Gasca
School of Natural Sciences, Autonomous University of Querétaro
Galina P Zaitzeva
Retired Professor of Medical Immunology. Universidad de Guadalajara. Mexico
Sally Priester
Médicos por la Verdad Puerto Rico
María J Martínez Albarracín
Retired Professor of Clinical Diagnostic Processes. University of Murcia. Spain
Alejandro Sousa-Escandon
Hospital Comarcal de Monforte, University of Santiago de Compostela, Spain
Fernando López Mirones
Biólogos por la Verdad, España
Bartomeu Payeras Cifre
Retired Biologist. University of Barcelona. Specialized in Microbiology. Spain
Almudena Zaragoza Velilla
Biólogos por la Verdad, España
Leopoldo M Borini
Epidemiólogos Argentinos Metadisciplinarios
Mario Mas
Epidemiólogos Argentinos Metadisciplinarios
Ramiro Salazar
Epidemiólogos Argentinos Metadisciplinarios
Edgardo Schinder
Epidemiólogos Argentinos Metadisciplinarios
Eduardo A Yahbes
Epidemiólogos Argentinos Metadisciplinarios
Marcela Witt
Epidemiólogos Argentinos Metadisciplinarios
Mariana Salmeron
Epidemiólogos Argentinos Metadisciplinarios
Patricia Fernández
Epidemiólogos Argentinos Metadisciplinarios
Miriam M Marchesini
Epidemiólogos Argentinos Metadisciplinarios
Alberto J Kajihara
Epidemiólogos Argentinos Metadisciplinarios
Marisol V De La Riva
Epidemiólogos Argentinos Metadisciplinarios
Patricia J Chimeno
Epidemiólogos Argentinos Metadisciplinarios
Paola A Grellet
Epidemiólogos Argentinos Metadisciplinarios
Matelda Lisdero
Epidemiólogos Argentinos Metadisciplinarios
Pamela Mas
Epidemiólogos Argentinos Metadisciplinarios
Abelardo J Gatica Baudo
Center for Integrative Medicine MICAEL (Medicina Integrativa Centro Antroposófico Educando en Libertad). Argentina
Elisabeth Retamoza
Center for Integrative Medicine MICAEL (Medicina Integrativa Centro Antroposófico Educando en Libertad). Argentina
Oscar Botta
Médicos por la Verdad Argentina
Chinda C Brandolino
Médicos por la Verdad Argentina
Javier Sciuto
Médicos por la Verdad Uruguay
Mario Cabrera Avivar
Médicos por la Verdad Uruguay
Mauricio Castillo
Médicos por la Libertad Chile
Patricio Villarroel
Médicos por la Libertad Chile
Emilia P Poblete Rojas
Médicos por la Libertad Chile
Bárbara Aguayo
Médicos por la Libertad Chile
Dan I Macías Flores
Médicos por la Libertad Chile
Jose V Rossell
Physician, orthopedic specialist. Chile
Julio C Sarmiento
Médicos por la Verdad Perú
Victor Andrade-Sotomayor
Médicos por la Verdad Perú
Wilfredo R Stokes Baltazar
Médicos por la Verdad Guatemala
Virna Cedeño Escobar
Centro de Biotecnologías Ómicas (CEBIOMICS) - Concepto Azul, Ecuador
Ulises Arrúa
Médicos por la Verdad Brasil
Atilio Farina del Río
Médicos por la Verdad Paraguay
Tatiana Campos Esquivel
Médicos por la Verdad Costa Rica
Patricia Callisperis
Médicos por la Verdad Bolivia
María Eugenia Barrientos
Médicos por la Verdad El Salvador
Christian Fiala
Gynmed Ambulatorium, Vienna. Austria
Karina Acevedo-Whitehouse
Author Profile

Abstract

Since the start of the COVID-19 outbreak, the race for testing new platforms designed to confer immunity against SARS-CoV-2, has been rampant and unprecedented, leading to conditional emergency authorization of various vaccines. Despite progress on early multidrug therapy for COVID-19 patients, the current mandate is to immunize the world population as quickly as possible. The lack of thorough testing in animals prior to clinical trials, and authorization based on safety data generated during trials that lasted less than 3.5 months, raise questions regarding vaccine safety. The recently identified role of SARS-CoV-2 Spike glycoprotein for inducing endothelial damage characteristic of COVID-19, even in absence of infection, is extremely relevant given that most of the authorized vaccines induce endogenous production of Spike. Given the high rate of occurrence of adverse effects that have been reported to date, as well as the potential for vaccine-driven disease enhancement, Th2-immunopathology, autoimmunity, and immune evasion, there is a need for a better understanding of the benefits and risks of mass vaccination, particularly in groups excluded from clinical trials. Despite calls for caution, the risks of SARS-CoV-2 vaccination have been minimized or ignored by health organizations and government authorities. As for any investigational biomedical program, data safety monitoring boards (DSMB) and event adjudication committees (EAC), should be enacting risk mitigation. If DSMBs and EACs do not do so, we will call for a pause in mass vaccination. If DSMBs and EACs do not exist, then vaccination should be halted immediately, in particular for demographic groups at highest risk of vaccine-associated death or serious adverse effects, during such time as it takes to assemble these boards and commence critical and independent assessments. We urge for pluralistic dialogue in the context of health policies, emphasizing critical questions that require urgent answers, particularly if we wish to avoid a global erosion of public confidence in science and public health.