Introduction
The global prevalence of type 2 diabetes mellitus (T2 DM), an essential
risk factor for coronary artery disease (CAD), is on the rise (1, 2). On
the other hand, CAD as a major cause of morbidity, mortality, and
financial costs in patients with T2DM, could be asymptomatic in 20–35%
of diabetic patients (3). However, acute myocardial infarction (MI) and
sudden cardiac death might be often the initial presentations (4, 5).
Developing at a younger age, higher rate of multi-vessel disease and
being more prone to have complications after MI, such as congestive
heart failure, are some of the features indicating the overall poorer
outcome of CAD in diabetic patients (6-8). This further emphasizes the
importance of detecting CAD at an early stage in these patients (9). It
has been suggested that myocardial perfusion imaging (MPI) is a reliable
technique for risk assessment of CAD in diabetic patients (10-12). It is
still under debate whether screening myocardial ischemia is rational in
asymptomatic diabetic patients compared to standard therapeutic
strategies and whether it improves the risk stratification, management,
and prognosis in different patient groups (4). Therefore, the aim of
this study was to assess CAD risk, prevalence and Predicting Factors of
an Abnormal Gated Myocardial Perfusion SPECT in Asymptomatic Patients
with Type 2 Diabetes .