COVER LETTER .
To,
The Editor-in-Chief,
Pediatric Blood & Cancer
Dear Sir/Madam,
We are happy to make the first submission submit of our researcharticle with the title “Is it safe to remove central lines in patients
with platelets less than 20,000/uL”.
We have no conflict of interest to disclose.
We have no suggestions for potential reviewers. We have no preferences
for reviewers.
Central line associated infections may be very difficult to control
without removing the lines. Yet, there is very little information
published on the safety and complications associated with removing
central lines in patients with very low platelets. We have reviewed the
complications associated with removal of central lines at very low
platelets.
Our findings suggest that it is safe to remove central lines even at
very low platelets. We found that lines could be removed safely even
with the cover of random donor platelets at very low platelet counts.
The place of removing the lines made no difference and removing lines
under sedation on bedside was safe. We also found no difference in
response between those patients who had antibiotics escalation and those
who did not. Our findings suggest that removing central line at
relatively low platelets even with limited cover of platelets infusion
is safe and effective. We believe these findings are of particular
relevance for the readers of PBC who may be faced with the dilemma of
central line removal in febrile neutropenic patients. We assessed that
our findings are best suited for the readers of PBC and thus the first
submission of our findings is being made to PBC.
We hope that PBC finds our work interesting and worth sharing with its
readers.
Thank you and kind regards,