RESULTS
Over the 15 year study period, there were 1,456 patients diagnosed with
hematologic malignancies at TCH: 981 with ALL, 173 with AML, and 302
with lymphoma. The HIM search provided a list of 365 potential patients
that met our ICD9 code inclusion criteria for both hematologic
malignancy and IMI. After medical record review, 61 patients (4.2%) met
criteria for pre-HSCT proven or probable IMI as defined by the
EORTC/MSG, including 8 cases of probable IMI and 53 cases of proven IMI.
The incidence of IMI varied by cancer diagnosis, with highest incidence
in AML (11/173, 6.4%), then ALL (45/981, 4.6%), and lowest incidence
in children with lymphoma (5/302, 1.7%). The distribution of patient
characteristics who were diagnosed with leukemia or lymphoma between
2006 and 2019 is shown in Table 1 , compared with the subset who
were also diagnosed with IMI, showing a higher likelihood of AML and
lower likelihood of lymphoma in the IMI subgroup.