Fungal isolates pre- and post-implementation of the TCH antifungal algorithm
Fifty-three out of 61 IMI cases diagnosed from 2006-2020 had a proven IMI: 47 had a single mold isolate, and six (11.3%) had multiple mold organisms isolated. The most common mold observed overall wasAspergillus species (n=19; 35.8%). All Aspergillus IMI occurred prior to algorithm implementation, as did all of the cases with multiple organisms isolated. The absence of Aspergillus cases from 2016-2020 was further verified by reviewing the mold isolate log in the TCH Microbiology laboratory Infectious Disease database. Post-algorithm implementation, the most common molds isolated includedTrichosporon (n=5) and Rhizopus (n=4) among the total of 14 molds identified from 2016 to 2020 (Table 4 ).