Acknowledgements
This research was supported by the US National Institute of General Medical Sciences (NIGMS/NIH) grant R01GM100482 to KF, the Wellcome Trust grant 209250/Z/17/Z and the Leibniz Association Leibniz Science Campus InterACt grant W6/2018, funded by the BWFGB Hamburg and the Leibniz Association (MT), Stanford Bio-X (to R.D. and R.C.K.); Stanford Gerald J. Lieberman Fellowship (to R.R.); the National Institutes of Health (R35 GM122579 to R.D.), the Howard Hughes Medical Institute (HHMI, to R.D.). This article is subject to HHMI’s Open Access to Publications policy. HHMI lab heads have previously granted a nonexclusive CC BY 4.0 license to the public and a sublicensable license to HHMI in their research articles. Pursuant to those licenses, the author-accepted manuscript of this article can be made freely available under a CC BY 4.0 license immediately upon publication. The authors thank Dr. Adam Zemla for the insightful conversations regarding the application of the LGA program to RNA structures.