3.1.Relationship between clinicopathological data and survival
When the pathological tumor stage and survival was compared, respective number of patients in stages 1 (n=5: 22.7%), 2 (n=1: 16.7%), 3 (n=8: 36.4%), 4A (n=12: 35.3%), and 4B (n=12: 80%) lost their lives. According to log -rank test, a significant negative correlation was observed between advanced pathological stage and OS (p=0.001) (Figure 1). Twenty-one (61.8%) patients with LNM and 17 (26.6%) cases without metastasis exited. A significant negative correlation was observed between the presence of LNM and OS (p<0.001) (Figure 2).
Tumor locations and survival rates were also compared. Indicated number of patients with glottic (n=20:31.3%), supraglottic (n= 12: 54.5%), transglottic (n= 5:41.7%) tumors, and one patient with subglottic tumor lost their lives. There was no statistically significant relationship between OS and tumor location (p=0.123, log-rank test).
Thirteen (59.1%) cases with, and 25 (32.5%) without PNI did not survive. There was a significant negative correlation between the presence of PNI and OS (p = 0.007). Twelve (48%) patients with, and 26 (35.1%) without LVI died. Fourteen (46.7%) cases with, and 24 (34.8%) without detectable necrosis exited. There was no significant relationship between OS, LVI and necrosis (p=0.337, p=0.107, respectively).