Statistical analysis:
The data that support the findings of this study are available from the corresponding author upon reasonable request. Some data may not be made available because of privacy or ethical restrictions. All experiments were designed, where possible, to generate groups of equal size. Power calculations were used to estimate the group size based on an expected effect size of 30%. Where possible, blinding and randomisation protocols were used. All data in the text and figures are presented as mean ± standard error mean (SEM) of n observations, wheren represents the number of animals studied (in vivo ) or independent values, not technical replicates (in vitro ). Exclusion criteria was pre-determined before the beginning of experiment, if there was blood in the peritoneal at harvest an individual n would be excluded, or at analysis stage outliners were defined as greater than +/- 2 SD from the mean. For western blot data, all data are represented as fold change compared to mean control. All statistical analysis was calculated using GraphPad Prism 7 for Mac (GraphPad Software, San Diego, California, USA; RRID:SCR_002798). Statistical analysis was only undertaken for studies where each group size was at least n = 4. For western blot analysis, representative data are shown where group size is n = 3. When the mean of two experimental groups were compared, a two‐tailed Studentst ‐test was performed. Normally distributed data without repeated measurements were assessed by a one‐way ANOVA followed by Bonferroni correction if the F value reached significance. In all cases aP < 0.05 was deemed significant.