Lung pathologic findings |
Patient 1 |
Patient
2 |
Patient 3 |
Patient 4 |
Patient 5 |
Patient 6 |
Patient 7 |
Interstitial/alveolar edema |
No lung tissue |
NI |
Present |
NI |
NI |
No lung tissue |
NI |
Capillary microthrombi |
– |
Present |
NI |
Present |
NI |
– |
NI |
Desquamation |
– |
Present |
Present |
Present |
Present |
– |
Present |
Hyaline membrane
formation
|
–
|
Present
|
Present
|
Present
|
Present
|
–
|
NI
|
Hyaline membrane organization |
– |
NI |
NI |
Present |
NI |
– |
NI |
Type II pneumocyte proliferation |
– |
Present |
Present |
NI |
Present |
– |
Present |
Cytopathic effect |
– |
Present |
Present |
NI |
NI |
– |
NI |
Interstitial cell increase |
– |
Present |
Present |
Present |
Present |
– |
Minimal |
Septal collagen increase |
– |
NI |
NI |
NI |
NI |
– |
Present |
Septal thickening |
– |
Present |
Present |
Present |
Present |
– |
Present |
Mononuclear cell increase |
– |
Minimal |
Present |
NI |
Minimal |
– |
NI |
Pathologic diagnosis |
|
DAD (Epithelial and vascular) |
DAD
(Epithelial) |
DAD (Epithelial and vascular) |
DAD (Epithelial) |
– |
DAD (vascular and fibrotic) |