Conclusions
The present study demonstrated that a single bolus injection of heparin
(100 U/kg) without ACT measurement was an effective and safe
intra-procedural anticoagulation regimen in patients with uninterrupted
NOACs undergoing CBA, which had a relatively short LA indwelling time.
With the current increase in NOAC administration and CBA, our results
would be helpful in determining the peri-procedural anticoagulation
strategy. Further large-scaled RCTs are required to clarity the
uncertainty about an optimal appropriate (intra-procedural
anticoagulation management under the condition of uninterrupted NOACs.