RESULTS
A total of 120 patients were enrolled into this prospective study (Group 1, n=60; Group 2, n=60). While the median (IQR) age was 66.5 (51-80) years in group 1 it was 67 (52-85) years in group 2 (p = 0.692). There was no statisticall significant regarding the preoperative parameters including PSA levels, prostate volume, ASA score, Q max, IPSS, QoL and PVR values between the two groups. While 20 % of the cases in group 1 and 31.7% in group 2 underwent prostate biopsy before HoLEP procedure use of antithrombotic agent was present in 13.3% and 21.7% of the cases in Group 1 and 2 respectively. There was no significant difference between both groups in terms of biopsy and antithrombotic therapy rates (p = 0.144 and p = 0.230, respectively) (Table 1). Preoperative data obtained in both groups are being given in Table 2. Evaluation of these parameters did not show major differences with respect to laser device used. While the median enucleation efficiency values in Group 1 and Group 2 were 1.15 (IQR: 0.33-2.2) and 1.11 (IQR: 0.4-2.8), median morcellation efficiency in both groups were 4.45 (IQR: 2.2-8) and 4.53 (IQR: 1.1-10), respectively. No statistically significant difference was noted with respect to these parameters in between groups (p = 0.775 and p = 0.204, respectively). Median values of hemoglobin decrease in Group 1 and Group 2 were 1.3 (IQR: 0.1-4) and 1.4 (IQR: 0.4-3.1), respectively (p = 0.736). No blood transfusion was required in any case of the patients in both groups. In our clinical practice, the routine catheterization time is two days, and the hospitalization period is three days. The duration of catheter removal for two patients in the group 1 and three patients in the group 2 was three days due to hematuria. Statistical evaluation of the data obtained revealed no significant difference between Group 1 and Group 2 in terms of catheterization and hospitalization (p = 0.649 and p = 0.649, respectively) (Table 2). A multiple linear regression analysis was performed to predict Hb decrease biopsy requirement, use of antithrombotic, and the type of laser devices variables (Table 3). Based on this evaluation, a positive and statistically significant correlation was found between biopsy anamnesis and Hb decrease (p = 0.002). However, no correlation could be demonstrated between Hb decrease and the type of laser device as well as antithrombotic use on this aspect (p = 0.906, p = 0.637, respectively). Median preoperative Qmax was 8.3 ml/s and this value increased to 28 ml/s 3 months after surgery (p < 0.001). Median baseline PVR value improved from 140 ml to 30 ml during 3 months evaluation (p < 0.001). Similarly, significant improvement was noted in IPSS and QoL scores after 3 months following the surgery.