Statistical analysis
Descriptive statistics were used to report means with standard deviation
and percentages. Multivariate binary logistic regression was used to
identify predictors of DDI (category 1 or 2) occurrence including number
of prescribed drugs, length of ICU stay, and patient gender and age.
Number of prescribed drugs and length of ICU stay were dichotomized by
the median for analysis.
DDIs in a similar cohort of patients in the cardiac intensive care (CCU)
at KTH, Pakistan from a previously published study 11was analyzed using criteria similar to current study and the number of
DDIs were compared using independent samples t-test. To maintain
consistency with the prior analysis, prevalence of category 1 and 2 DDI
were compared between the two institutions. Statistical analyses were
performed using IBM SPPS Statistics for Windows, Version 25 (Armonk, NY:
IBM Corp.).