Statistical analysis
Descriptive statistics were used to report means with standard deviation and percentages. Multivariate binary logistic regression was used to identify predictors of DDI (category 1 or 2) occurrence including number of prescribed drugs, length of ICU stay, and patient gender and age. Number of prescribed drugs and length of ICU stay were dichotomized by the median for analysis.
DDIs in a similar cohort of patients in the cardiac intensive care (CCU) at KTH, Pakistan from a previously published study 11was analyzed using criteria similar to current study and the number of DDIs were compared using independent samples t-test. To maintain consistency with the prior analysis, prevalence of category 1 and 2 DDI were compared between the two institutions. Statistical analyses were performed using IBM SPPS Statistics for Windows, Version 25 (Armonk, NY: IBM Corp.).