Results:
The frequency of clinically significant hypoglycaemia (blood glucose < 3 mmol/L) during the 4 week period of SMBG was 38.8%, while the frequency of severe hypoglycaemia over the last one year was 22.5%. Based on the Gold score and Clarke score, 28.3% and 24.6% of subjects respectively had IAH. The Clarke score was associated with increased frequency of clinically significant hypoglycaemia, severe hypoglycaemia and hospitalizations for hypoglycaemia. Prior group education, education from a dietitian and education on blood glucose targets were associated with lower Clarke scores, while adjusting insulin doses for blood glucose using an insulin sensitivity factor was associated with lower Gold and Clarke scores.