Limitations
At the preliminary stage of designing this study, we aimed to
investigate the correlation of the degree of MS severity and
echocardiographic parameters of RV function through multivariate
analysis, independent of PAP values. However, we were unable to identify
and include the sufficient number of patients with various degrees of MS
severity (who met our inclusion/exclusion criteria) necessary for
providing a significantly meaningful multivariate analysis on severe and
very severe subgroups, while accounting for and eliminating the effect
of PAP.