Limitations
At the preliminary stage of designing this study, we aimed to investigate the correlation of the degree of MS severity and echocardiographic parameters of RV function through multivariate analysis, independent of PAP values. However, we were unable to identify and include the sufficient number of patients with various degrees of MS severity (who met our inclusion/exclusion criteria) necessary for providing a significantly meaningful multivariate analysis on severe and very severe subgroups, while accounting for and eliminating the effect of PAP.