Prevalence of PIMs
A ccording to AGS updated Beers criteria2019, a total of 62.4%
(n=156) patients were prescribed with at least one PIM as identified by
Beers criteria 2019. The details of the overall prevalence of PIMs use
in older adult patients hospitalized with cardiovascular disease, as
specified in the present study, are shown in Table 2. The most common
identified PIMs in the study cohort were Proton pump inhibitor,
Short-acting insulin according to the sliding scale, Enoxaparin, to name
a few. Overall, 8.8% (n=22) of the patients were prescribed with at
least ≥ 3 PIMs, as described in table 1.
On Bivariate logistic regression, Gender female (OR 2.36, 95% CI 1.36-
4.09; P= 0.002), three diagnosis (OR 4.29, 95% CI 1.31- 14.0; P=0.016),
≥4 diagnosis (OR 4.8, 95% CI 1.49- 15.44; P= 0.009), 7-9 days of
hospital stay (OR 4.74, 95% CI 1.07- 20.96; P= 0.04), 5-8 medications
(OR 0.08, 95% CI 0.01- 0.40; P= 0.002), ≥ 9 medications (OR 0.09, 95%
CI 0.01- 0.50; P= 0.006), CrCl 31- 60ml/min (OR 0.38, 95% CI 0.19-
0.75; P= 0.006), CrCl 61- 90 ml/min (OR 0.15, 95% CI 0.07- 0.32; P=
<0.001) were found to be important predictors for the
potentially inappropriate prescribing in older adult patients. The
predictors analysed for PIMs prescribing are summarised in Table 3.