Prevalence of PIMs
A ccording to AGS updated Beers criteria2019, a total of 62.4% (n=156) patients were prescribed with at least one PIM as identified by Beers criteria 2019. The details of the overall prevalence of PIMs use in older adult patients hospitalized with cardiovascular disease, as specified in the present study, are shown in Table 2. The most common identified PIMs in the study cohort were Proton pump inhibitor, Short-acting insulin according to the sliding scale, Enoxaparin, to name a few. Overall, 8.8% (n=22) of the patients were prescribed with at least ≥ 3 PIMs, as described in table 1.
On Bivariate logistic regression, Gender female (OR 2.36, 95% CI 1.36- 4.09; P= 0.002), three diagnosis (OR 4.29, 95% CI 1.31- 14.0; P=0.016), ≥4 diagnosis (OR 4.8, 95% CI 1.49- 15.44; P= 0.009), 7-9 days of hospital stay (OR 4.74, 95% CI 1.07- 20.96; P= 0.04), 5-8 medications (OR 0.08, 95% CI 0.01- 0.40; P= 0.002), ≥ 9 medications (OR 0.09, 95% CI 0.01- 0.50; P= 0.006), CrCl 31- 60ml/min (OR 0.38, 95% CI 0.19- 0.75; P= 0.006), CrCl 61- 90 ml/min (OR 0.15, 95% CI 0.07- 0.32; P= <0.001) were found to be important predictors for the potentially inappropriate prescribing in older adult patients. The predictors analysed for PIMs prescribing are summarised in Table 3.