Abstract
Aim: The aim of this study was to investigate the relationship
between umbilical cord blood neutrophil gelatinase-associated lipocalin
and neonatal diseases, such as acute kidney injury.
Materials and Method: The neutrophil gelatinase-associated
lipocalin levels were measured in umbilical cord blood of 180 babies
born in the department of Obstetrics and Gynecology between 2015-2016.
Patients were classified according to maternal diseases, neonatal
diseases, and demographic features. The obtained data were compared with
umbilical cord blood neutrophil gelatinase-associated lipocalin levels.
Results: There was a statistically significant difference
between umbilical cord blood NGAL levels and premature rupture of
membranes (p<0.05), ABO incompatibility (p<0.05),
meconium aspiration syndrome (p<0.001), ventricular septal
defect (p<0.001), and breech presentation birth
(p<0.001).
Conclusion: neutrophil gelatinase-associated lipocalin can be
useful as a diagnostic biomarker in the evaluation of maternal and
neonatal diseases. However, further studies on larger patient
populations are needed.