Conclusion
Due to reduced immunity and increased disease susceptibility, mixed vaginitis is prone to occur during pregnancy. A positive glucose tolerance test during pregnancy and a history of vaginitis during pregnancy are risk factors for mixed vaginitis in late pregnancy. The symptoms and signs of women with mixed vaginitis during pregnancy are difficult to distinguish from women with simple vaginitis and are related to the adverse outcome of puerperal infection. It is recommended to efficiently distinguish mixed vaginitis through laboratory examination. Therefore, vaginitis should be diagnosed and treated during early pregnancy, and blood glucose management should be guided in time during pregnancy to prevent puerperal infection.
Conflicts of Interest: The authors declare no conflict of interest.
Financial disclosure: The authors declare no financial disclosures.
Author’ Contributions: All authors fulfilled the conditions required for authorship and have approved this submission. HL, CH, and FX conceived the study question, and all authors were involved in the study design. HL, and YY were involved in the statistical analysis while HL, MD,and WX interpreted the results. HL created the first draft of the manuscript. MD, WX, WQ, FT, HL, and CW made substantial contributions to drafting the article and revising it critically. Furthermore, all authors have given their final approval for this version to be published and agree to be accountable for all aspects of the work.
Acknowledgements: Not applicable.
Ethics approval:This project was approved by the Ethics Committee of Tianjin Medical University General Hospital. (Ethical NO. IRB2020-WZ-194, 15 December 2020)
Funding: This work was supported by Tianjin Municipal Science and Technology Commission Special Foundation for Science and Technology Major Projects in Control and Prevention of Major Diseases (Grant No. 18ZXDBSY00200), General Project of the National Natural Science Foundation of China (Grant No. 82071674) and Tianjin Health Science and Technology Project (Grant No. KJ20003).
Supporting Information:Additional supporting information may be found online in the Supporting Information section at the end of the article.
Table 1. Comparison socio-demographic characteristics of mixed vaginitis with single vaginitis during pregnancy.
Table 2. Risk factors associated with mixed vaginitis during pregnancy.
Table 3. Comparison clinical symptoms and signs and laboratory characteristics of mixed vaginitis with single vaginitis during pregnancy.
Table 4. Comparison pregnancy outcomes of mixed vaginitis with single vaginitis.
Table S1. Prevalence of single and mixed vaginitis in pregnancy peoples.