2.3 Treatment schedules
The repeated drug therapy of CSDS
mice was implemented once daily at 9:30 a.m.—10:30 a.m. in time of the
last 14 days. The doses chosen were based on the behavioral consequences
and previous records (Xu, Wang, Zhao, Gao, & Cui, 2017). All these
compounds were stereotactic injected into the bilateral nucleus
accumbens (NAc). Control mice were given the corresponding vehicle, also
in the parallel volume.