Treatment with E2, ICI 182,780, or LPS individually or in combination does not modulate monocyte CD11b or TLR4 in neonates or adults
Next, we examined the effect of E2, ICI 182,780, or LPS individually or in combination and stratified the samples by sex in order to determine if there are any sex-specific differences in expression of CD11b or TLR4 in CD14+ monocytes from adult blood or UCB. Figure 3 shows that neither CD11b or TLR4 surface antigens differed between sexes in expression following treatment and there were no statistically significant differences overall.