Sex-specific differences in adult monocyte ER-β expression in
response to ICI 182,780 treatment
We determined the effects of E2, ICI 182,780, or LPS on ER-α or ER-β
expression. Neither ER-α or ER-β showed statistically significant
differences in expression between the sexes following treatment or
overall, however there was a general trend towards higher ER-α and ER-β
expression adult females compared to adult males (Figure 2; panels B,
D). A statistically significant difference between male versus female
adults was observed in ER-β monocyte receptor expression following ICI
182,780 treatment (p<0.05).