Cover Letter
Date: 03/06/2021
Dr Charles Young, Editor-in-Chief, International Journal of
Clinical Practice
Re: Short Communication: Prevalence and Impact of Takotsubo
Syndrome in Hospitalizations for Acute Ischemic Stroke
Dear Dr. Young,
We herewith submit a Short Communication entitled “Prevalence and
Impact of Takotsubo Syndrome in Hospitalizations for Acute Ischemic
Stroke” for possible publication in your esteemed journal after your
kind review.
Upcoming reports suggest Acute Ischemic Stroke is one of the known
triggers to TTS. The acute cerebral events including acute ischemic
stroke (AIS) are associated with catecholamine surge and hence, can lead
to TTS. However, limited data exist on the prevalence and outcomes of
TTS in AIS. Furthermore, the impact of TTS on in-hospital outcomes of
AIS remains unexplored. Using the National Inpatient Sample (2007-2014)
databases and relevant ICD-9 CM codes, we identified AIS and TTS-related
adult hospitalizations and assessed the frequency of TTS in AIS patients
and its impact on disposition of patients and healthcare resource
utilization in the United States.
We hope the editorial board and reviewers will find the content suitable
for International Journal of Clinical Practice. This manuscript,
as submitted or its essence in another version is not under
consideration for publication elsewhere and will not be published
elsewhere while under consideration by International Journal of
Clinical Practice. The authors have no commercial associations or
sources of support that might pose a conflict of interest. All authors
have made substantive contributions to the manuscript, and all authors
endorse the data and conclusions.
We have no relationships with industry to disclose.
Thank you for your consideration.
Yours sincerely,
Rupak Desai, MBBS
Division of Cardiology
Atlanta Veterans Affairs Medical Center, 1670 Clairmont Rd, Decatur, GA
30033
Email:rdesa30@emory.eduPhone: (404) 321-6111 ext. 7359