Introduction
MANEC is a neoplasm characterized by significant histological
heterogeneity and is characterized by the simultaneous presence of both
adenocarcinomatous and neuroendocrine differentiation; their definition
includes each component found in at least 30% of the tumor. (1) They
most commonly arise in the colon, appendix, rectum or stomach, however,
a limited number of MANECs have been reported to originate in the
gallbladder. (2) Due to the low frequency of this histotype, only a
small number of cases have been described, and there is no established
therapeutic strategy. Here we present a case of the patient with MANEC
of anal region.