What does this article add?
• Only the baseline Ca level was observed as the potential predictor of the efficacy of MWA (P <0.05).
• Ca level as insignificant to construct a mathematical model to predict the efficacy of MWA (P = 0.071).
• A significant difference in time differences was observed after 1 day of the MWA treatments in the levels of Ca, P, and PHT except than ALP, those of which was 30 days later (P <0.001). Later on, the difference stayed steady until the end of follow up.
• MW ablation was found safe and effective treatment method in the treatment of PHPT, and it can reduce Ca and PTH levels and nodule size when the treatment success considered.