3. Results
3.1. Possible predictors of the efficacy of
MWA
Investigation of the possible predictors was conducted on 32 patients.
The response group had 28 patients while no response groups had the 4
patients. Only statistically significant difference was observed at the
baseline serum Ca levels of the two groups (P <0.05).
No statistically significant any other differences were observed between
the two groups for the rest of the other characteristics which are
summarized in Table 2.
3.2. Investigation of the efficacy of predictors for MWA
efficacy
Baseline levels of Ca were analyzed by using logistic regression in
order to show the predictive role of it as MWA efficacy on PHPT
patients. However, the results of univariate logistic regression
analysis revealed no statistically significant difference, and a
predictive model has not been constructed to show the predictive role of
baseline Ca level on the response for the PHPT patients (P =0.071).
3.3. Treatment outcomes and
effect
Figure 1 presents the results of the six-month follow up median values
for Ca, ALP, P, and PTH values. Investigation of Figure 3 demonstrates
that changes in the followed parameters were statistically significant
compared to baseline (P <0.001) (Figure 1) in different
times. An obvious statistically significant decrease was observed for
the median values of Ca (2.9 mmol/L) and PTH (99.50 ng/L) while that of
P (0.9 mmol/L) was decreased in 1 day after MWA therapy. On the other
hand, no significant change was observed in ALP (82.00 u/L) at 1 day
after MWA. A statically significant difference was obtained after one
month later in the ALP levels (P <0.001). The detailed results
were also summarized in Table 3.
3.4. Side effect of
complications
Most patients experienced a slight tingling and pain sensation in the
neck, but this was well tolerated without causing interruption or
termination of the procedure. Six patients (18.75%) reported transit
voice change, but this resolved without any specific treatment within
one day. All in all, flexible fiberoptic laryngoscopy examination was
normal. This transit complication was attributable to lidocaine which
was used for hydrodissection. One case of cellulitis requiring drainage
and antibiotics was developed. There were no major complications
requiring hospitalization.