Introduction
Coronary heart disease (CHD) has been a hot spot in cardiovascular
disease research. It is a heart disease caused by the formation of
coronary atherosclerotic plaque, which result in stenosis or obstruction
of the vascular lumen, leading to myocardial ischemia, hypoxia and
necrosis. According to the report published in 2016, CHD accounts for
20% of deaths in Europe, and is still one of the diseases with the
highest morbidity and mortality in the
world[1,2].
CHD involving three vessels disease (TVD) is a more extensive and
serious disease than common CHD, and the change of left ventricular (LV)
function was earlier than that of structure. The main function of the LV
is to transport blood to all parts of the body and undertake the blood
supply to the whole body. So the effective evaluation of LV function in
patients with TVD is very meaningful to the treatment and prognosis of
patients. Traditional echocardiography has become the first choice for
clinicians to diagnose heart disease, but it is less sensitive in early
identification of cardiac function
changes[3]. The
three-dimensional speckle tracking echocardiography (3D-STE) is a
quantitative tool to evaluate LV function with high accuracy and
reliability[4].
Nesser et al.[5]found that 3D-STE in assessment of LV systolic function had a remarkable
correlation with cardiac MRI. 3D-STE can provide more cardiac function
evaluation indexes for clinical and detect LV subclinical myocardial
injury early[6-8].
This study used 3D-STE to quantitatively analyze the changes of systolic
LV strain parameters and evaluate LV function in patients with TVD
without myocardial infarction.