Three-dimensional speckle tracking echocardiography in
evaluating left ventricular function in patients with triple vessel
coronary artery disease
CUI Xiu-xiu, DONG Yu, WANG Ying, CHANG Wen-xing, LI Ying, YU Ting-ting,
LI Guang-sen*
Department of Ultrasound, The Second Affiliated Hospital of Dalian
Medical University,
Dalian, Liaoning 116027, China
Abstract: AIM Using three-dimensional ultrasound speckle
tracking echocardiography (3D-STE) to evaluate left ventricular (LV)
function in patients with triple vessel coronary artery disease(TVD)
without myocardial infarction. METHODS Sixty patients with TVD
without myocardial infarction were divided into two groups according to
the results of coronary angiography. Group B (n=31):50%≤the stenosis
rate of all triple vessel coronary artery<75%; Group C (n=29):the
stenosis rate of all triple vessel coronary artery≥75%. Thirty healthy
subjects were recruited as the group A. We measured LV end-diastolic and
end-systolic volume (LVEDV, LVESV) and LV ejection fraction (LVEF) using
real-time dynamic
three-dimensional echocardiography. The 3D-STE parameters of LV included
global longitudinal strain (GLS), global area strain (GAS), global
radial strain (GRS) and global circumferential strain (GCS). The
correlation between 3D-STE parameters and NT-proBNP were analyzed byPearson linear correlation analysis. RESULTS In group C,
LVEDV and LVESV were significantly increased (all P <0.05), while
LVEF, GLS, GRS, GCS and GAS were significantly decreased compared with
groups A and B (all P <0.05). In groups A and B, there were no
statistical differences in LVEDV, LVESV and LVEF. However, GLS, GCS and
GAS were lower in group B than in group A (all P <0.05). The
correlation analysis showed a negative correlation between the absolute
values of GLS, GRS, GCS, GAS and NT-proBNP in group C
(r =-0.866、-0.587、-0.428、-0.600,P <0.001、P =0.001、P =0.020、P =0.010).CONCLUSIONS Our study shows that 3D-STE can evaluate the LV
function in patients with triple vessel coronary artery disease without
myocardial infarction through multiple strain parameters.
Key words: Three-dimensional speckle tracking echocardiography,
Coronary artery disease, triple vessel coronary artery disease,Left
ventricular function, NT-proBNP