MATERIALS AND METHODS
Patient selection and inclusion/exclusion criteria
204 patients with middle ear cholesteatoma diagnosed by me from January 2018 to October 2019 were all the subjects of this study. The research scheme approved by the appropriate institutional review committee is taken as the scheme for this experiment. The criteria of this study are mainly confirmed patients with chronic otitis media with cholesteatoma in the upper tympanic cavity, aged 6-80 years, without maxillary sinus or mastoid involvement. To confirm the disease, it is necessary to pass preoperative high-resolution computed tomography (HRCT) of temporal bone and otoendoscopy, and general anesthesia is necessary during operation. We have followed the “Specifying the target difference in the primary outcome for a randomised controlled trial: guidance for researchers” reporting guidelines for the preparation of this paper.
All patients underwent pure tone audiometry, tympanometry, and preoperative HRCT scans of temporal bone before surgery (Figure 1). Thirteen patients with mastoid dilatation need to be thoroughly cleared of diseases, and must be thoroughly treated by undergoing surgery under the tube wall. In addition, the patients excluded from the research and analysis were one case of lateral semicircular canal fistula found during operation.
Patients who received EES and micro-otosurgery (MES) were randomly divided into two groups by random number table. One of the randomized sequences generated by a random number table is used to hide and distribute sealed opaque envelopes. Among them, the author will perform all cases of surgery to ensure the consistency of the study.