Legends of tables
Table 1. Summary table reporting hemodynamic, autonomic and
electrophysiological effects of 20 hERG blockers (Supplemental Figures 1
to 105). All drugs were tested at the first dose level causing either
QTc prolongation and/or increase in HFQT oscillations or change in
autonomic control. 5 torsadogenic hERG blockers were tested at a higher
dose (lower panel). Changes highlighted in black refer to changes that
reached statistical significance threshold when compared to vehicle.
Table 2. Summary table reporting changes in autonomic biomarkers in LQT1
and LQT2 patients with QTc prolongation versus patients with concealed
QTc prolongation and in LQT1 and LQT2 patients with concealed QTc
prolongation versus healthy subjects. Supplemental Figures 127 to 134.