Legends of tables
Table 1. Summary table reporting hemodynamic, autonomic and electrophysiological effects of 20 hERG blockers (Supplemental Figures 1 to 105). All drugs were tested at the first dose level causing either QTc prolongation and/or increase in HFQT oscillations or change in autonomic control. 5 torsadogenic hERG blockers were tested at a higher dose (lower panel). Changes highlighted in black refer to changes that reached statistical significance threshold when compared to vehicle.
Table 2. Summary table reporting changes in autonomic biomarkers in LQT1 and LQT2 patients with QTc prolongation versus patients with concealed QTc prolongation and in LQT1 and LQT2 patients with concealed QTc prolongation versus healthy subjects. Supplemental Figures 127 to 134.