Figure 3. The distribution of all 31 positive detections comprising 15 different microbial species, detected by either method in 25 samples. A total of 55% findings were detectable with the T2Bacteria Panel. If contaminants are excluded, the T2Bacteria Panel covers 77% of clinically relevant findings.
The implementation of the T2Bacteria Panel decreased the time to species identification on average by 55 hours. The mean time from arrival to the laboratory to species identification was 6.1 hours (SD±5.4) for T2Bacteria Panel and 62 hours (SD±54) for the conventional BC-based identification (P = 0.001). The mean time from arrival to negative result was 7.4 hours (SD±7) for T2Bacteria Panel and 119 hours (SD±56) for the conventional BC (P < 0.001).
Rapid identification with the T2Bacteria Panel permitted early antimicrobial stewardship interventions related to faster time to detection and/or new finding of BSI pathogen and early initiation of targeted antibiotic therapy. Interventions were made in 9 of 15 patients with T2Bacteria Panel positive samples as seen on Table 1. T2Bacteria Panel negative results were not evaluated for this analysis.