Figure 3. The distribution of all 31 positive detections
comprising 15 different microbial species, detected by either method in
25 samples. A total of 55% findings were detectable with the T2Bacteria
Panel. If contaminants are excluded, the T2Bacteria Panel covers 77% of
clinically relevant findings.
The implementation of the T2Bacteria Panel decreased the time to species
identification on average by 55 hours. The mean time from arrival to the
laboratory to species identification was 6.1 hours (SD±5.4) for
T2Bacteria Panel and 62 hours (SD±54) for the conventional BC-based
identification (P = 0.001). The mean time from arrival to negative
result was 7.4 hours (SD±7) for T2Bacteria Panel and 119 hours (SD±56)
for the conventional BC (P < 0.001).
Rapid identification with the T2Bacteria Panel permitted early
antimicrobial stewardship interventions related to faster time to
detection and/or new finding of BSI pathogen and early initiation of
targeted antibiotic therapy. Interventions were made in 9 of 15 patients
with T2Bacteria Panel positive samples as seen on Table 1. T2Bacteria
Panel negative results were not evaluated for this analysis.