3.4.3 CRP clearance effect
Twenty-one studies compared the impact of CRRT group and control group
on CRP clearance effect. Due to large heterogeneity
(I2=96.4%), random effects model was used for
analysis, and
the
results showed that the difference was statistically significant, that
compared with the control treatment group, patients treated with CRRT
had significantly higher CRP clearance effect. (WMD=-8.25, 95%CI-9.74
to -6.76, P<0.00001)(Fig.5). We conducted a subgroup analysis
according to the clinical CRP value, and divided the CRP value 1-5 into
a group, which was the normal value. CRP values of 5-50 were divided
into a group, indicating the presence of mild and moderate inflammation
in the body. CRP above 50 was divided into a group, suggesting severe
inflammation in the body.