2.3 Inclusion Criteria
(1)Research type: Randomized controlled trials (RCTS), whether blind or not, have no language limitations.(2)Research objects: Up to AP diagnostic criteria4.(3)Intervention measures: The control group received routine treatment, including water abstinence, fasting, gastrointestinal decompression, acid inhibition, enzyme inhibition, catharsis, pain relief, anti-infection and nutritional support, as well as symptomatic treatment such as mechanical ventilation and anti-shock when necessary. The CRRT group was treated with continuous veno-venous hemofiltration on the basis of conventional treatment. None of the patients underwent surgery.(4)Outcome measurement index: mortality rate of AP patients, serum amylase, TNF-α, CRP,PCT, IL-6 clearance rate, liver and kidney function, APACHE II score after treatment.