3.3.2 | BPD at 36 weeks
Twelve trials 14-21,23-26 involving 1831 newborns
reported the incidence of BPD at 36 weeks. Meta-analysis revealed that
MISA techniques brought about a significant decrease in this outcome (RR
: 0.59, 95% CI : 0.46 to 0.75, I2 = 3%, p
< .0001). Sensitivity analysis limited to studies that
unequivocally stated the use of the INSURE regimen in the control group
showed similar results (RR : 0.59, 95% CI : 0.45 to 0.78,
I2 = 20%, p = .0002, 10 studies15-18,20,21,23-26 (n = 1400)) (Figure 2B).