Table 1- Baseline characteristics of patients with GFR <60 vs. patients with GFR ≥60
Variable
GFR <60 N = 339 GFR ≥60 N = 317
p value
Age (years)* 73.6 ± 13.3 67.1 ± 15.4 <0.001
Gender 0.015
Men 154 (45%) 174 (55%)
Women 185 (55%) 143 (45%)
African-American 271 (80%) 258 (81%) 0.639
Latino 61 (18%) 51 (16%) 0.517
BMI (kg/m2)+ 27.5 (9.5) 27.6 (9.1) 0.433
Hypertension 315 (93%) 255 (80%) <0.001
Dyslipidemia 136 (40%) 117 (37%) 0.383
Smoking 116 (35%) 145 (46%) 0.003
DM 134 (40%) 85 (27%) <0.001
CAD 80 (24%) 56 (18%) 0.067
PVD 34 (10%) 27 (9%) 0.506
CHF 113 (34%) 90 (29%) 0.198
Prior stroke 77 (23%) 54 (17%) 0.076
CHADVasc2 <0.001
0 5 (1%) 22 (7%)
1 18 (5%) 41 (13%)
>1 316 (93%) 254 (80%)
Oral Hypogly 65 (19%) 43 (14%) 0.053
Insulin 46 (14%) 13 (4%) <0.001
Aspirin 140 (41%) 129 (41%) 0.850
Plavix 24 (7%) 15 (5%) 0.204
Statins 124 (37%) 112 (35%) 0.739
Β-Blockers 155 (46%) 136 (43%) 0.447
ACEI/ARB 146 (43%) 144 (45%) 0.543
Coumadin/AC 133 (39%) 135 (43%) 0.383
% Time on AC+ 62.7 (43.0) 60.4 (33.0) 0.551
Digoxin 42 (12%) 37 (12%) 0.778
Amiodarone 8 (2%) 3 (1%) 0.159
BiDil 20 (6%) 7 (2%) 0.017
CCB-DH 82 (24%) 64 (20%) 0.218
CCB-NonDH 45 (13%) 25 (8%) 0.026
Abbreviations: ACEI Angiotensin converting enzyme; ARB Angiotensin receptor blocker; BMI body mass index; GFR glomerular filtration rate. * Mean ± SD, Two-sample t-test + Median (IQR), Wilcoxon Rank Sum test N (%), Chi-square test otherwise Abbreviations: ACEI Angiotensin converting enzyme; ARB Angiotensin receptor blocker; BMI body mass index; GFR glomerular filtration rate. * Mean ± SD, Two-sample t-test + Median (IQR), Wilcoxon Rank Sum test N (%), Chi-square test otherwise Abbreviations: ACEI Angiotensin converting enzyme; ARB Angiotensin receptor blocker; BMI body mass index; GFR glomerular filtration rate. * Mean ± SD, Two-sample t-test + Median (IQR), Wilcoxon Rank Sum test N (%), Chi-square test otherwise Abbreviations: ACEI Angiotensin converting enzyme; ARB Angiotensin receptor blocker; BMI body mass index; GFR glomerular filtration rate. * Mean ± SD, Two-sample t-test + Median (IQR), Wilcoxon Rank Sum test N (%), Chi-square test otherwise