Study population
This study included adult patients with CVID meeting the European
Society for Immunodeficiency (ESID)/International Consensus Document
(ICON) diagnostic criteria , and vaccination was indicated by the
attending immunologist and performed by specialized vaccination centers.
Patients with pre-vaccination reverse transcription polymerase chain
reaction (RT-PCR)-confirmed SASRS-CoV-2 infection or severe
non-infectious complications were excluded. Their results were compared
with those of corresponding sex- and age-matched healthy controls (HCs).