References
Ago J, Ishikawa T, Matsumoto N, Ashequr Rahman M, & Kamei C (2006).
Mechanism of imipramine-induced seizures in amygdala-kindled rats.
Epilepsy research 72: 1-9.
Alachkar A, Azimullah S, Lotfy M, Adeghate E, Ojha SK, Beiram R,
et al. (2020). Antagonism of Histamine H3 receptors Alleviates
Pentylenetetrazole-Induced Kindling and Associated Memory Deficits by
Mitigating Oxidative Stress, Central Neurotransmitters, and c-Fos
Protein Expression in Rats. Molecules (Basel, Switzerland) 25.
Alachkar A, Azimullah S, Ojha SK, Beiram R, Łażewska D, Kieć-Kononowicz
K, et al. (2019). The Neuroprotective Effects of Histamine H3
Receptor Antagonist E177 on Pilocarpine-Induced Status Epilepticus in
Rats. Molecules (Basel, Switzerland) 24.
Alachkar A, Latacz G, Siwek A, Lubelska A, Honkisz E, Gryboś A, et
al. (2018a). Anticonvulsant evaluation of novel non-imidazole histamine
H3R antagonists in different convulsion models in rats. Pharmacology,
biochemistry, and behavior 170: 14-24.
Alachkar A, Łażewska D, Latacz G, Frank A, Siwek A, Lubelska A, et
al. (2018b). Studies on Anticonvulsant Effects of Novel Histamine H3R
Antagonists in Electrically and Chemically Induced Seizures in Rats.
International journal of molecular sciences 19.
Arrang JM, Garbarg M, & Schwartz JC (1983). Auto-inhibition of brain
histamine release mediated by a novel class (H3) of histamine receptor.
Nature 302: 832-837.
Bañuelos-Cabrera I, Cuéllar-Herrera M, Velasco AL, Velasco F,
Alonso-Vanegas M, Carmona F, et al. (2016). Pharmacoresistant
temporal lobe epilepsy modifies histamine turnover and H3 receptor
function in the human hippocampus and temporal neocortex. Epilepsia
57: e76-80.
Bastaki SM, Abdulrazzaq YM, Shafiullah M, Więcek M, Kieć-Kononowicz K,
& Sadek B (2018). Anticonvulsant and reproductive toxicological studies
of the imidazole-based histamine H3R antagonist 2-18 in mice. Drug
design, development and therapy 12: 179-194.
Bertram EH (2013). Neuronal circuits in epilepsy: do they matter? Exp
Neurol 244: 67-74.
Bhowmik M, Saini N, & Vohora D (2014). Histamine H3 receptor antagonism
by ABT-239 attenuates kainic acid induced excitotoxicity in mice. Brain
research 1581: 129-140.
Cakmak YO (2006). Epilepsy, electroacupuncture and the nucleus of the
solitary tract. Acupuncture in medicine : journal of the British Medical
Acupuncture Society 24: 164-168.
Carrasco MA, Jaimovich E, Kemmerling U, & Hidalgo C (2004). Signal
transduction and gene expression regulated by calcium release from
internal stores in excitable cells. Biological research 37:701-712.
Catterall WA (2014). Sodium channels, inherited epilepsy, and
antiepileptic drugs. Annual review of pharmacology and toxicology
54: 317-338.
Cerminara C, El-Malhany N, Roberto D, Lo Castro A, & Curatolo P (2013).
Seizures induced by desloratadine, a second-generation antihistamine:
clinical observations. Neuropediatrics 44: 222-224.
Chen GF, Ren GL, Zhang LS, & Hu XY (2012). [Effects of Wuling mycelia
on pentylenetetrazole-induced epilepsy in rats]. Zhejiang da xue xue
bao Yi xue ban = Journal of Zhejiang University Medical sciences
41: 647-652.
Chen K, Wang JJ, Yung WH, Chan YS, & Chow BK (2005). Excitatory effect
of histamine on neuronal activity of rat globus pallidus by activation
of H2 receptors in vitro. Neuroscience research 53: 288-297.
Chen Z, Li WD, Zhu LJ, Shen YJ, & Wei EQ (2002). Effects of histidine,
a precursor of histamine, on pentylenetetrazole-induced seizures in
rats. Acta pharmacologica Sinica 23: 361-366.
Chen Z, Sakurai E, Hu W, Jin C, Kiso Y, Kato M, et al. (2004).
Pharmacological effects of carcinine on histaminergic neurons in the
brain. British journal of pharmacology 143: 573-580.
Cilz NI, & Lei S (2017). Histamine facilitates GABAergic transmission
in the rat entorhinal cortex: Roles of H(1) and H(2) receptors, Na(+)
-permeable cation channels, and inward rectifier K(+) channels.
Hippocampus 27: 613-631.
Cogé F, Guénin SP, Rique H, Boutin JA, & Galizzi JP (2001). Structure
and expression of the human histamine H4-receptor gene. Biochemical and
biophysical research communications 284: 301-309.
Collart Dutilleul P, Ryvlin P, Kahane P, Vercueil L, Semah F, Biraben
A, et al. (2016). Exploratory Phase II Trial to Evaluate the
Safety and the Antiepileptic Effect of Pitolisant (BF2.649) in
Refractory Partial Seizures, Given as Adjunctive Treatment During 3
Months. Clinical neuropharmacology 39: 188-193.
Connelly WM, Shenton FC, Lethbridge N, Leurs R, Waldvogel HJ, Faull
RL, et al. (2009). The histamine H4 receptor is functionally
expressed on neurons in the mammalian CNS. British journal of
pharmacology 157: 55-63.
Dai H, Fu Q, Shen Y, Hu W, Zhang Z, Timmerman H, et al. (2007).
The histamine H3 receptor antagonist clobenpropit enhances GABA release
to protect against NMDA-induced excitotoxicity through the cAMP/protein
kinase A pathway in cultured cortical neurons. European journal of
pharmacology 563: 117-123.
Dai YJ, Wu DC, Feng B, Hou WW, Xu CL, Ohtsu H, et al. (2015).
Protective effect of carnosine on febrile seizures in immature mice.
Neuroscience letters 588: 95-100.
De Luca R, Suvorava T, Yang D, Baumgärtel W, Kojda G, Haas HL, et
al. (2016). Identification of histaminergic neurons through histamine 3
receptor-mediated autoinhibition. Neuropharmacology 106:102-115.
Desmadryl G, Gaboyard-Niay S, Brugeaud A, Travo C, Broussy A, Saleur
A, et al. (2012). Histamine H4 receptor antagonists as potent
modulators of mammalian vestibular primary neuron excitability. British
journal of pharmacology 167: 905-916.
Ellenbroek BA, & Ghiabi B (2014). The other side of the histamine H3
receptor. Trends in neurosciences 37: 191-199.
Engel J, Jr. (2018). The current place of epilepsy surgery. Current
opinion in neurology 31: 192-197.
Enrique AV, Di Ianni ME, Goicoechea S, Lazarowski A, Valle-Dorado MG,
Costa JJL, et al. (2019). New anticonvulsant candidates prevent
P-glycoprotein (P-gp) overexpression in a pharmacoresistant seizure
model in mice. Epilepsy & behavior : E&B: 106451.
Erickson JD, Schafer MK, Bonner TI, Eiden LE, & Weihe E (1996).
Distinct pharmacological properties and distribution in neurons and
endocrine cells of two isoforms of the human vesicular monoamine
transporter. Proceedings of the National Academy of Sciences of the
United States of America 93: 5166-5171.
Feng HJ, & Faingold CL (2000). Modulation of audiogenic seizures by
histamine and adenosine receptors in the inferior colliculus.
Experimental neurology 163: 264-270.
Feng HJ, Naritoku DK, Randall ME, & Faingold CL (2001). Modulation of
audiogenically kindled seizures by gamma-aminobutyric acid-related
mechanisms in the amygdala. Experimental neurology 172:477-481.
Fernandes CEM, & Serafim KR (2019). Systemic injection of an H4
receptor agonist induces a decrease in CREB and pCREB levels in the
cerebellar vermis and prefrontal cortex in mice. 52: e8334.
Fernandes CEM, Serafim KR, Gianlorenco ACL, & Mattioli R (2017).
Intra-vermis H4 receptor agonist impairs performance in anxiety- and
fear-mediated models. Brain research bulletin 135: 179-184.
Fujii Y, Tanaka T, Harada C, Hirai T, & Kamei C (2003). Epileptogenic
activity induced by histamine H(1) antagonists in amygdala-kindled rats.
Brain research 991: 258-261.
Gholipoor P, Saboory E, Roshan-Milani S, & Fereidoni J (2013). Effect
of hyperthermia on histamine blood level and convulsive behavior in
infant rats. Epilepsy & behavior : E&B 29: 269-274.
Giovannini MG, Efoudebe M, Passani MB, Baldi E, Bucherelli C, Giachi
F, et al. (2003). Improvement in fear memory by
histamine-elicited ERK2 activation in hippocampal CA3 cells. The Journal
of neuroscience : the official journal of the Society for Neuroscience
23: 9016-9023.
Haas HL, Sergeeva OA, & Selbach O (2008). Histamine in the nervous
system. Physiological reviews 88: 1183-1241.
Harada C, Fujii Y, Hirai T, Shinomiya K, & Kamei C (2004). Inhibitory
effect of iodophenpropit, a selective histamine H3 antagonist, on
amygdaloid kindled seizures. Brain research bulletin 63:143-146.
Harada C, Hirai T, Fujii Y, Harusawa S, Kurihara T, & Kamei C (2004).
Intracerebroventricular administration of histamine H3 receptor
antagonists decreases seizures in rat models of epilepsia. Methods and
findings in experimental and clinical pharmacology 26: 263-270.
Harwell V, & Fasinu PS (2020). Pitolisant and Other Histamine-3
Receptor Antagonists-An Update on Therapeutic Potentials and Clinical
Prospects. Medicines (Basel, Switzerland) 7.
Ishikawa T, Takechi K, Rahman A, Ago J, Matsumoto N, Murakami A,
et al. (2007). Influences of histamine H1 receptor antagonists on
maximal electroshock seizure in infant rats. Biological &
pharmaceutical bulletin 30: 477-480.
Jahan K, Pillai KK, & Vohora D (2017). Parachlorophenylalanine-induced
5-HT depletion alters behavioral and brain neurotransmitters levels in
6-Hz psychomotor seizure model in mice. Fundamental & clinical
pharmacology 31: 403-410.
Jang IS, Rhee JS, Watanabe T, Akaike N, & Akaike N (2001).
Histaminergic modulation of GABAergic transmission in rat ventromedial
hypothalamic neurones. The Journal of physiology 534: 791-803.
Ji MJ, Zhang XY, Peng XC, Zhang YX, Chen Z, Yu L, et al. (2018).
Histamine Excites Rat GABAergic Ventral Pallidum Neurons via
Co-activation of H1 and H2 Receptors. Neuroscience bulletin 34:1029-1036.
Jia F, Kato M, Dai H, Xu A, Okuda T, Sakurai E, et al. (2006).
Effects of histamine H(3) antagonists and donepezil on learning and
mnemonic deficits induced by pentylenetetrazol kindling in weanling
mice. Neuropharmacology 50: 404-411.
Jin C, Lintunen M, & Panula P (2005). Histamine H(1) and H(3) receptors
in the rat thalamus and their modulation after systemic kainic acid
administration. Experimental neurology 194: 43-56.
Jin CL, Zhuge ZB, Wu DC, Zhu YY, Wang S, Luo JH, et al. (2007).
Lesion of the tuberomammillary nucleus E2-region attenuates postictal
seizure protection in rats. Epilepsy research 73: 250-258.
Kaeberle J (2018). Epilepsy Disorders and Treatment Modalities. NASN
school nurse (Print) 33: 342-344.
Kamei C, Ishizawa K, Kakinoki H, & Fukunaga M (1998). Histaminergic
mechanisms in amygdaloid-kindled seizures in rats. Epilepsy research
30: 187-194.
Karlstedt K, Sallmén T, Eriksson KS, Lintunen M, Couraud PO, Joó
F, et al. (1999). Lack of histamine synthesis and down-regulation
of H1 and H2 receptor mRNA levels by dexamethasone in cerebral
endothelial cells. Journal of cerebral blood flow and metabolism :
official journal of the International Society of Cerebral Blood Flow and
Metabolism 19: 321-330.
Kasteleijn-Nolst Trenité D, Parain D, Genton P, Masnou P, Schwartz JC,
& Hirsch E (2013). Efficacy of the histamine 3 receptor (H3R)
antagonist pitolisant (formerly known as tiprolisant; BF2.649) in
epilepsy: dose-dependent effects in the human photosensitivity model.
Epilepsy & behavior : E&B 28: 66-70.
Katoh Y, Niimi M, Yamamoto Y, Kawamura T, Morimoto-Ishizuka T, Sawada
M, et al. (2001). Histamine production by cultured microglial
cells of the mouse. Neuroscience letters 305: 181-184.
Khateb A, Fort P, Pegna A, Jones BE, & Mühlethaler M (1995).
Cholinergic nucleus basalis neurons are excited by histamine in vitro.
Neuroscience 69: 495-506.
Kim CK, Adhikari A, & Deisseroth K (2017). Integration of optogenetics
with complementary methodologies in systems neuroscience. Nature reviews
Neuroscience 18: 222-235.
Korotkova TM, Haas HL, & Brown RE (2002). Histamine excites GABAergic
cells in the rat substantia nigra and ventral tegmental area in vitro.
Neuroscience letters 320: 133-136.
Kukko-Lukjanov TK, Grönman M, Lintunen M, Laurén HB, Michelsen KA,
Panula P, et al. (2012). Histamine 1 receptor knock out mice show
age-dependent susceptibility to status epilepticus and consequent
neuronal damage. Epilepsy research 100: 80-92.
Kukko-Lukjanov TK, Lintunen M, Jalava N, Laurén HB, Lopez-Picon FR,
Michelsen KA, et al. (2010). Involvement of histamine 1 receptor
in seizure susceptibility and neuroprotection in immature mice. Epilepsy
research 90: 8-15.
Kwiatkowski H (1943). Histamine in nervous tissue. The Journal of
physiology 102: 32-41.
Löscher W (2011). Critical review of current animal models of seizures
and epilepsy used in the discovery and development of new antiepileptic
drugs. Seizure 20: 359-368.
Löscher W, Klitgaard H, Twyman RE, & Schmidt D (2013). New avenues for
anti-epileptic drug discovery and development. Nature reviews Drug
discovery 12: 757-776.
Labarinas S, Meulmester K, Greene S, Thomas J, Virk M, & Erkonen G
(2018). Extracorporeal Cardiopulmonary Resuscitation After
Diphenhydramine Ingestion. Journal of medical toxicology : official
journal of the American College of Medical Toxicology 14:253-256.
Łażewska D, Kaleta M, Hagenow S, Mogilski S, Latacz G, Karcz T, et
al. (2018). Novel naphthyloxy derivatives - Potent histamine H(3)
receptor ligands. Synthesis and pharmacological evaluation. Bioorganic
& medicinal chemistry 26: 2573-2585.
Lein E, Borm LE, & Linnarsson S (2017). The promise of spatial
transcriptomics for neuroscience in the era of molecular cell typing.
Science 358: 64-69.
Leurs R, Traiffort E, Arrang JM, Tardivel-Lacombe J, Ruat M, & Schwartz
JC (1994). Guinea pig histamine H1 receptor. II. Stable expression in
Chinese hamster ovary cells reveals the interaction with three major
signal transduction pathways. Journal of neurochemistry 62:519-527.
Li B, Zhang XY, Yang AH, Peng XC, Chen ZP, Zhou JY, et al.(2016). Histamine Increases Neuronal Excitability and Sensitivity of the
Lateral Vestibular Nucleus and Promotes Motor Behaviors via HCN Channel
Coupled to H2 Receptor. Frontiers in cellular neuroscience 10:300.
Li D, Carozza RB, Shatos MA, Hodges RR, & Dartt DA (2012). Effect of
histamine on Ca(2+)-dependent signaling pathways in rat conjunctival
goblet cells. Investigative ophthalmology & visual science 53:6928-6938.
Li Q, Jin CL, Xu LS, Zhu-Ge ZB, Yang LX, Liu LY, et al. (2005).
Histidine enhances carbamazepine action against seizures and improves
spatial memory deficits induced by chronic transauricular kindling in
rats. Acta pharmacologica Sinica 26: 1297-1302.
Li Q, Liu LY, Zhu YY, Zhou WX, & Chen Z (2006). [Effect of chronic
transauricular kindled seizures on passive-avoidance test memory
retention in rats]. Zhejiang da xue xue bao Yi xue ban = Journal of
Zhejiang University Medical sciences 35: 419-423.
Lintunen M, Sallmen T, Karlstedt K, & Panula P (2005). Transient
changes in the limbic histaminergic system after systemic kainic
acid-induced seizures. Neurobiology of disease 20: 155-169.
Liu B, Zhang X, Wang C, Zhang G, & Zhang H (2008). Antihistamine
mepyramine directly inhibits KCNQ/M channel and depolarizes rat superior
cervical ganglion neurons. Neuropharmacology 54: 629-639.
Lovenberg TW, Roland BL, Wilson SJ, Jiang X, Pyati J, Huvar A, et
al. (1999). Cloning and functional expression of the human histamine H3
receptor. Molecular pharmacology 55: 1101-1107.
Lundius EG, Sanchez-Alavez M, Ghochani Y, Klaus J, & Tabarean IV
(2010). Histamine influences body temperature by acting at H1 and H3
receptors on distinct populations of preoptic neurons. The Journal of
neuroscience : the official journal of the Society for Neuroscience
30: 4369-4381.
Manz KM, Becker JC, Grueter CA, & Grueter BA (2020). Histamine H(3)
Receptor Function Biases Excitatory Gain in the Nucleus Accumbens.
Biological psychiatry.
Meller S, Brandt C, Theilmann W, Klein J, & Löscher W (2019).
Commonalities and differences in extracellular levels of hippocampal
acetylcholine and amino acid neurotransmitters during status epilepticus
and subsequent epileptogenesis in two rat models of temporal lobe
epilepsy. Brain research 1712: 109-123.
Midzyanovskaya IS, & Tuomisto L (2003). Increased density of H1
histamine receptors in brain regions of rats with absence epilepsy.
Inflammation research : official journal of the European Histamine
Research Society [et al] 52 Suppl 1: S29-30.
Nectow AR, & Nestler EJ (2020). Viral tools for neuroscience. Nature
reviews Neuroscience 21: 669-681.
Nishida N, Huang ZL, Mikuni N, Miura Y, Urade Y, & Hashimoto N (2007).
Deep brain stimulation of the posterior hypothalamus activates the
histaminergic system to exert antiepileptic effect in rat
pentylenetetrazol model. Experimental neurology 205: 132-144.
Onodera K, Tuomisto L, Tacke U, & Airaksinen M (1992). Strain
differences in regional brain histamine levels between genetically
epilepsy-prone and resistant rats. Methods and findings in experimental
and clinical pharmacology 14: 13-16.
Peng SY, Zhuang QX, He YC, Zhu JN, & Wang JJ (2013). Histamine excites
neurons of the inferior vestibular nucleus in rats by activation of H1
and H2 receptors. Neuroscience letters 541: 87-92.
Potschka H (2012). Animal models of drug-resistant epilepsy. Epileptic
disorders : international epilepsy journal with videotape 14:226-234.
Qin YT, Ma SH, Zhuang QX, Qiu YH, Li B, Peng YP, et al. (2011).
Histamine evokes excitatory response of neurons in the cerebellar
dentate nucleus via H2 receptors. Neuroscience letters 502:133-137.
Raible DG, Lenahan T, Fayvilevich Y, Kosinski R, & Schulman ES (1994).
Pharmacologic characterization of a novel histamine receptor on human
eosinophils. American journal of respiratory and critical care medicine
149: 1506-1511.
Sáez ME, González-Pérez A, Gaist D, Johansson S, Nagy P, & García
Rodríguez LA (2016). Risk of seizure associated with use of
acid-suppressive drugs: An observational cohort study. Epilepsy &
behavior : E&B 62: 72-80.
Sadek B, Kuder K, Subramanian D, Shafiullah M, Stark H, Lażewska
D, et al. (2014a). Anticonvulsive effect of nonimidazole
histamine H3 receptor antagonists. Behavioural pharmacology 25:245-252.
Sadek B, Saad A, Latacz G, Kuder K, Olejarz A, Karcz T, et al.(2016). Non-imidazole-based histamine H3 receptor antagonists with
anticonvulsant activity in different seizure models in male adult rats.
Drug design, development and therapy 10: 3879-3898.
Sadek B, Saad A, Sadeq A, Jalal F, & Stark H (2016). Histamine H3
receptor as a potential target for cognitive symptoms in
neuropsychiatric diseases. Behavioural brain research 312:415-430.
Sadek B, Saad A, Schwed JS, Weizel L, Walter M, & Stark H (2016).
Anticonvulsant effects of isomeric nonimidazole histamine H(3) receptor
antagonists. Drug design, development and therapy 10:3633-3651.
Sadek B, Saad A, Subramanian D, Shafiullah M, Łażewska D, &
Kieć-Kononowiczc K (2016). Anticonvulsant and procognitive properties of
the non-imidazole histamine H3 receptor antagonist DL77 in male adult
rats. Neuropharmacology 106: 46-55.
Sadek B, Schwed JS, Subramanian D, Weizel L, Walter M, Adem A, et
al. (2014b). Non-imidazole histamine H3 receptor ligands incorporating
antiepileptic moieties. European journal of medicinal chemistry
77: 269-279.
Sadek B, Shehab S, Więcek M, Subramanian D, Shafiullah M,
Kieć-Kononowicz K, et al. (2013). Anticonvulsant properties of
histamine H3 receptor ligands belonging to N-substituted carbamates of
imidazopropanol. Bioorganic & medicinal chemistry letters 23:4886-4891.
Samotaeva IS, Birioukova LM, Midzyanovskaya IS, Kuznetsova GD, Bazyan
AS, & Tuomisto L (2012). Metoprine induced behavioral modifications and
brain regional histamine increase in WAG/Rij and Wistar rats. Epilepsy
research 101: 148-156.
Sanna MD, Borgonetti V, Masini E, & Galeotti N (2020). Histamine H(4)
receptor stimulation in the locus coeruleus attenuates neuropathic pain
by promoting the coeruleospinal noradrenergic inhibitory pathway.
European journal of pharmacology 868: 172859.
Sanna MD, Ghelardini C, Thurmond RL, Masini E, & Galeotti N (2017).
Behavioural phenotype of histamine H(4) receptor knockout mice: Focus on
central neuronal functions. Neuropharmacology 114: 48-57.
Sanna MD, Mello T, Masini E, & Galeotti N (2018). Activation of
ERK/CREB pathway in noradrenergic neurons contributes to
hypernociceptive phenotype in H4 receptor knockout mice after nerve
injury. Neuropharmacology 128: 340-350.
Schaper F, Plantinga BR, Colon AJ, Wagner GL, Boon P, Blom N, et
al. (2020). Deep Brain Stimulation in Epilepsy: A Role for Modulation
of the Mammillothalamic Tract in Seizure Control? Neurosurgery
87: 602-610.
Schneider EH, Neumann D, & Seifert R (2014). Modulation of behavior by
the histaminergic system: lessons from H(1)R-and H(2)R-deficient mice.
Neuroscience and biobehavioral reviews 42: 252-266.
Schneider EH, & Seifert R (2016). The histamine H4-receptor and the
central and peripheral nervous system: A critical analysis of the
literature. Neuropharmacology 106: 116-128.
Seeley N, & Sturman G (2001). Effect of amthamine, a histamine
H2-agonist, in two mouse chemical-induced seizure models. Inflammation
research : official journal of the European Histamine Research Society
[et al] 50 Suppl 2: S82-83.
Selbach O, Brown RE, & Haas HL (1997). Long-term increase of
hippocampal excitability by histamine and cyclic AMP. Neuropharmacology
36: 1539-1548.
Singh E, Pillai KK, & Mehndiratta M (2014). Characterization of a
lamotrigine-resistant kindled model of epilepsy in mice: evaluation of
drug resistance mechanisms. Basic & clinical pharmacology & toxicology
115: 373-378.
Song M, Yan R, Zhang Y, Guo D, Zhou N, & Deng X (2020). Design,
synthesis, and anticonvulsant effects evaluation of nonimidazole
histamine H(3) receptor antagonists/inverse agonists containing triazole
moiety. Journal of enzyme inhibition and medicinal chemistry
35: 1310-1321.
Stevens DR, Eriksson KS, Brown RE, & Haas HL (2001). The mechanism of
spontaneous firing in histamine neurons. Behavioural brain research
124: 105-112.
Sturman G, Freeman P, & Quinn L (2001). Histamine H1-antagonists
potentiate seizures in the EL (epilepsy-like) mouse model of temporal
lobe epilepsy. Inflammation research : official journal of the European
Histamine Research Society [et al] 50 Suppl 2: S80-81.
Sugitate R, Okubo Y, Nariai H, & Matsui A (2020). The effects of
antihistamine on the duration of the febrile seizure: A single center
study with a systematic review and meta-analysis. Brain & development
42: 103-112.
Swiader M, Wielosz M, & Czuczwar SJ (2004). Influence of antazoline and
ketotifen on the anticonvulsant activity of conventional antiepileptics
against maximal electroshock in mice. European neuropsychopharmacology :
the journal of the European College of Neuropsychopharmacology
14: 307-318.
Swiader MJ, Porebiak J, Swiader K, Wielosz M, & Czuczwar SJ (2006).
Influence of cimetidine on the anticonvulsant activity of conventional
antiepileptic drugs against pentetrazole-induced seizures in mice.
Pharmacological reports : PR 58: 131-134.
Szczepanska K, Kuder K, & Kiec-Kononowicz K (2018). Histamine H3
Receptor Ligands in the Group of (Homo)piperazine Derivatives. Current
medicinal chemistry 25: 1609-1626.
Szyndler J, Piechal A, Blecharz-Klin K, Skórzewska A, Maciejak P,
Walkowiak J, et al. (2006). Effect of kindled seizures on rat
behavior in water Morris maze test and amino acid concentrations in
brain structures. Pharmacological reports : PR 58: 75-82.
Tian L, Wen YQ, Li HZ, Zuo CC, & Wang JJ (2000). Histamine excites rat
cerebellar Purkinje cells via H2 receptors in vitro. Neuroscience
research 36: 61-66.
Toyota H, Dugovic C, Koehl M, Laposky AD, Weber C, Ngo K, et al.(2002). Behavioral characterization of mice lacking histamine H(3)
receptors. Molecular pharmacology 62: 389-397.
Traiffort E, Vizuete ML, Tardivel-Lacombe J, Souil E, Schwartz JC, &
Ruat M (1995). The guinea pig histamine H2 receptor: gene cloning,
tissue expression and chromosomal localization of its human counterpart.
Biochemical and biophysical research communications 211:570-577.
Trinka E, Kwan P, Lee B, & Dash A (2019). Epilepsy in Asia: Disease
burden, management barriers, and challenges. Epilepsia 60 Suppl
1: 7-21.
Tuomisto L, Sturman G, Freeman P, & Tarhanen J (2003). Brain histamine
turnover and seizure behaviour in two mouse strains: preliminary
findings. Inflammation research : official journal of the European
Histamine Research Society [et al] 52 Suppl 1: S27-28.
van Loo KMJ, Rummel CK, Pitsch J, Müller JA, Bikbaev AF, Martinez-Chavez
E, et al. (2019). Calcium Channel Subunit α2δ4 Is Regulated by
Early Growth Response 1 and Facilitates Epileptogenesis. J Neurosci
39: 3175-3187.
Varaschin RK, Rosenberg MJ, Hamilton DA, & Savage DD (2014).
Differential effects of the histamine H(3) receptor agonist methimepip
on dentate granule cell excitability, paired-pulse plasticity and
long-term potentiation in prenatal alcohol-exposed rats. Alcoholism,
clinical and experimental research 38: 1902-1911.
Vinogradova LV, Shatskova AB, & Tuomisto L (2007). Histaminergic
modulation of acoustically induced running behavior in rats. Brain
research 1148: 198-204.
von Einsiedel RW, Roesch-Ely D, Diebold K, Sartor K, Mundt C, &
Bergemann N (2002). H(2)-histamine antagonist (famotidine) induced
adverse CNS reactions with long-standing secondary mania and epileptic
seizures. Pharmacopsychiatry 35: 152-154.
Wada Y, Shiraishi J, Nakamura M, & Koshino Y (1996). Biphasic action of
the histamine precursor L-histidine in the rat kindling model of
epilepsy. Neuroscience letters 204: 205-208.
Wang Y, & Chen Z (2019). An update for epilepsy research and
antiepileptic drug development: Toward precise circuit therapy.
Pharmacology & therapeutics 201: 77-93.
Wei F, Yan LM, Su T, He N, Lin ZJ, Wang J, et al. (2017). Ion
Channel Genes and Epilepsy: Functional Alteration, Pathogenic Potential,
and Mechanism of Epilepsy. Neuroscience bulletin 33: 455-477.
Wu DC, Zhu-Ge ZB, Yu CY, Fang Q, Wang S, Jin CL, et al. (2008).
Low-frequency stimulation of the tuberomammillary nucleus facilitates
electrical amygdaloid-kindling acquisition in Sprague-Dawley rats.
Neurobiology of disease 32: 151-156.
Xu X, Holmes TC, Luo MH, Beier KT, Horwitz GD, Zhao F, et al.(2020). Viral Vectors for Neural Circuit Mapping and Recent Advances in
Trans-synaptic Anterograde Tracers. Neuron 107: 1029-1047.
Yamada K, Takizawa F, Tamura T, & Kanda T (2012). The effect of
antihistamines on seizures induced by increasing-current electroshocks:
ketotifen, but not olopatadine, promotes the seizures in infant rats.
Biological & pharmaceutical bulletin 35: 693-697.
Yamakami J, Sakurai E, Kuramasu A, Sakurai E, Yanai K, Watanabe T,
et al. (2000). L-Histidine decarboxylase protein and activity in rat
brain microvascular endothelial cells. Inflammation research : official
journal of the European Histamine Research Society [et al]
49: 231-235.
Yamamoto Y, Lee D, Kim Y, Lee B, Seo C, Kawasaki H, et al.(2012). Raf kinase inhibitory protein is required for cerebellar
long-term synaptic depression by mediating PKC-dependent MAPK
activation. The Journal of neuroscience : the official journal of the
Society for Neuroscience 32: 14254-14264.
Yamanaka K, Gouraud SS, Takagishi M, Kohsaka A, Maeda M, & Waki H
(2017). Evidence for a histaminergic input from the ventral
tuberomammillary nucleus to the solitary tract nucleus involved in
arterial pressure regulation. Physiological reports 5.
Yan H, Zhang X, Hu W, Ma J, Hou W, Zhang X, et al. (2014).
Histamine H3 receptors aggravate cerebral ischaemic injury by
histamine-independent mechanisms. Nat Commun 5: 3334-3334.
Yasuhara A, Ochi A, Harada Y, & Kobayashi Y (1998). Infantile spasms
associated with a histamine H1 antagonist. Neuropediatrics 29:320-321.
Yawata I, Tanaka K, Nakagawa Y, Watanabe Y, Murashima YL, & Nakano K
(2004). Role of histaminergic neurons in development of epileptic
seizures in EL mice. Brain research Molecular brain research
132: 13-17.
Yazdi A, Doostmohammadi M, Pourhossein Majarshin F, & Beheshti S
(2020). Betahistine, prevents kindling, ameliorates the behavioral
comorbidities and neurodegeneration induced by pentylenetetrazole.
Epilepsy & behavior : E&B 105: 106956.
Yokoyama H, Hirose M, Uematsu M, Haginoya K, Iinuma K, & Kimura S
(2012). Ketotifen overdose in infancy associated with development of
epilepsy and mild mental retardation. Pediatrics international :
official journal of the Japan Pediatric Society 54: 963.
Yokoyama H, Iinuma K, Yanai K, Watanabe T, Sakurai E, & Onodera K
(1993). Proconvulsant effect of ketotifen, a histamine H1 antagonist,
confirmed by the use of d-chlorpheniramine with monitoring
electroencephalography. Methods and findings in experimental and
clinical pharmacology 15: 183-188.
Yokoyama H, Sato M, Iinuma K, Onodera K, & Watanabe T (1996). Centrally
acting histamine H1 antagonists promote the development of amygdala
kindling in rats. Neuroscience letters 217: 194-196.
Yoshida M, Noguchi E, & Tsuru N (2000). Lack of substantial effect of
the H(3)-antagonist thioperamide and of the non-selective mixed
H(3)-antagonist/H(1)-agonist betahistine on amygdaloid kindled seizures.
Epilepsy research 40: 141-145.
Yuan H, & Silberstein SD (2018). Histamine and Migraine. Headache
58: 184-193.
Yuan Y, & Isom LL (2014). SUMOylation of Neuronal K⁺ channels: a
potential therapeutic pathway for epilepsy and SUDEP? Neuron
83: 996-998.
Zhang L, Chen G, Chen J, He X, & Hu X (2017). [Mechanisms of
histamine ameliorating memory impairment induced by
pentylenetetrazole-kindling epilepsy in rats]. Zhejiang da xue xue bao
Yi xue ban = Journal of Zhejiang University Medical sciences
46: 1-6.
Zhang L, Chen Z, Ren K, Leurs R, Chen J, Zhang W, et al. (2003).
Effects of clobenpropit on pentylenetetrazole-kindled seizures in rats.
European journal of pharmacology 482: 169-175.
Zhang LS, Chen JF, Chen GF, Hu XY, & Ding MP (2013). Effects of
thioperamide on seizure development and memory impairment induced by
pentylenetetrazole-kindling epilepsy in rats. Chinese medical journal
126: 95-100.
Zhang LS, Chen Z, Huang YW, Hu WW, Wei EQ, & Yanai K (2003). Effects of
endogenous histamine on seizure development of
pentylenetetrazole-induced kindling in rats. Pharmacology 69:27-32.
Zhang LS, Ma YY, & Li Q (2006). [Effects of endogenous histamine on
memory impairment induced by pentylenetetrazole-kindled epilepsy in
rats]. Zhejiang da xue xue bao Yi xue ban = Journal of Zhejiang
University Medical sciences 35: 630-634.
Zhang LS, Shen HQ, Jin CL, Hu WW, Zhao MH, & Chen Z (2004).
[Mechanisms of the effect of brain histamine on chronic epilepsy
induced by pentylenetetrazole]. Zhejiang da xue xue bao Yi xue ban =
Journal of Zhejiang University Medical sciences 33: 201-204.
Zhang XY, Yu L, Zhuang QX, Peng SY, Zhu JN, & Wang JJ (2013).
Postsynaptic mechanisms underlying the excitatory action of histamine on
medial vestibular nucleus neurons in rats. British journal of
pharmacology 170: 156-169.
Zhao H, Lin Y, Chen S, Li X, & Huo H (2018). 5-HT3 Receptors: A
Potential Therapeutic Target for Epilepsy. Current neuropharmacology
16: 29-36.
Zhou FW, Xu JJ, Zhao Y, LeDoux MS, & Zhou FM (2006). Opposite functions
of histamine H1 and H2 receptors and H3 receptor in substantia nigra
pars reticulata. Journal of neurophysiology 96: 1581-1591.
Zhou J, Lee AW, Devidze N, Zhang Q, Kow LM, & Pfaff DW (2007).
Histamine-induced excitatory responses in mouse ventromedial
hypothalamic neurons: ionic mechanisms and estrogenic regulation.
Journal of neurophysiology 98: 3143-3152.
Zhou P, Homberg JR, Fang Q, Wang J, Li W, Meng X, et al. (2019).
Histamine-4 receptor antagonist JNJ7777120 inhibits pro-inflammatory
microglia and prevents the progression of Parkinson-like pathology and
behaviour in a rat model. Brain, behavior, and immunity 76:61-73.
Zhuang QX, Wu YH, Wu GY, Zhu JN, & Wang JJ (2013). Histamine excites
rat superior vestibular nuclear neurons via postsynaptic H1 and H2
receptors in vitro. Neuro-Signals 21: 174-183.
Zhuang QX, Xu HT, Lu XJ, Li B, Yung WH, Wang JJ, et al. (2018).
Histamine Excites Striatal Dopamine D1 and D2 Receptor-Expressing
Neurons via Postsynaptic H1 and H2 Receptors. Molecular neurobiology
55: 8059-8070.
Zolaly MA (2012). Histamine H1 antagonists and clinical characteristics
of febrile seizures. International journal of general medicine
5: 277-281.