Conclusion
The relationship between COX-2 expression and prognosis in some types of
cancer has been examined and different results have been reported. There
are insufficient studies investigating the relationship between Wilms
Tumor and COX-2 expression and prognosis.
In our study, there was no significant correlation between prognostic
parameters and COX-2 expression. COX-2 expression was observed in almost
all patients, so we think that the COX-2 pathway is effective during the
development phase of WT, also therefore it may be beneficial to add
COX-2 inhibitors to the treatment. However, it is necessary to support
this with larger-scale studies for more objective results.