Results of surgical treatment of moderate ischemic mitral regurgitation:
A propensity analysis
Background and Aim of the Study: Ischemic mitral valve regurgitation
(IMR) in patients undergoing coronary artery bypass grafting (CABG) is
associated with worse long-term outcomes. The aim of this study was to
assess the impact of mitral valve repair with CABG in patients with
moderate IMR. Method: This observational study enrolled 3,215
consecutive patients from the Juntendo CABG registry with moderate IMR
and multivessel coronary artery disease who underwent CABG between 2002
and 2017. The CABG alone and CABG with mitral valve surgery (MVs) groups
were compared. The propensity score was calculated for each patient.
Long-term all-cause death, cardiac death, and major adverse cardiac and
cerebrovascular events (MACCEs) were compared between the two groups.
Results: A total of 101 patients who underwent CABG had moderate IMR in
our database. Propensity score matching selected 40 pairs for final
analysis. MVs was associated with increased risks of postoperative
atrial fibrillation, blood transfusion, and longer hospitalization.
There were no differences between the two groups in long-term outcomes,
including all-cause mortality, cardiac mortality, and the incidence of
MACCEs. Conclusions: Surgical treatment of moderate IMR combined with
CABG was as safe as CABG alone, with no differences in long-term
outcomes. Further studies are needed to determine the effects of MVs in
patients with moderate IMR and severe coronary artery disease.